Searchable abstracts of presentations at key conferences in endocrinology

ea0016p730 | Thyroid | ECE2008

A poly A(−) RNA transcript (Heg) in human blood mononuclear cells is inversely related to TSH receptor autoantibodies in patients with untreated Graves' disease: gene expression of CD14 and inhibition of Cdk1

Christensen Niels Juel , Habekost Gurli , Bratholm Palle

Objective: We studied a previously uncharacterized poly A(−) RNA transcript (designated Heg) in blood mononuclear cells and its relationship to TSH receptor autoantibodies and to CD14, Nucks, Cdk1, GCRα, NF-κB and CK2 mRNA.Subjects and methods: The main study groups were a) normal subjects b) patients with early and untreated Graves’ disease and c) patients with Graves’ disease studied after treatment. Quantification of mRNA was...